Advantix Single Dose One Month Application Flea And Tick Control For Dogs 55 Lbs. And Over. Kills and repells fleas, ticks and mosquitoes. Stops flea bites within 3-5 minutes. Kills 98-100% of fleas in first 12 hours. Stays on if dog goes swimming or bathing. Do not use on cats. Contains Imidacloprid and Permethrin. Use on advise of Veterinarian. One month dose.